The sitcom, which ran for eight seasons, followed the sheriff of Mayberry, Andy Taylor (Griffith). At five years old, Howard played Opie during the duration of the series from 1960 to 1968. Knotts was known for his role as Deputy Sheriff Barney Fife — which won him five Emmys.

TV has so many great examples of brilliant partnerships, but when asked to name who I considered to be the top TV comedy duo of all time, my mind went to a fictional place that still feels so real — Mayberry,

Ron Howard, who found fame as a child star on the hit 1960s series “The Andy Griffith Show,” recently shared a photo on social media that showed him with his costars Andy Griffith and Don Knotts.