A 69-year-old St. Charles man was pronounced dead at the scene. Two other people were transported by ambulance in serious condition to a nearby hospital.

A fatal crash on Interstate 270 has shut down several lanes this afternoon, causing significant traffic disruptions.

The Missouri State Highway Patrol closed northbound Interstate 270 Tuesday afternoon for a crash that left a 69-year-old man dead. Officials reported that the crash happened on I-270 just north of ...

Crews are hard at work on a significant project to replace the aging bridges and the pavement where I-270 crosses the ...

ST. LOUIS COUNTY, Mo. — A man told police on March 30 he drove on Interstate 64 near Interstate 270 in St. Louis County when he passed a couple's car, cutting them off. Investigators said ...

The 133-acre Bellefontaine Conservation Area at Interstate 270 and Lewis and Clark Boulevard in north St. Louis County includes ... conservation planner for the Missouri Department of Conservation ...