Fred Hutch and MSK researchers showed that tumors driven by hiccups in RNA processing can't hid from the immune system. In ...

In 2021, research led by Ryan Flynn, MD, Ph.D., and his mentor, Nobel laureate Carolyn Bertozzi, Ph.D., opened a new chapter ...

These insights from researchers could have major implications for diseases like cancer, where gene expression goes awry.

Scientists at the Icahn School of Medicine at Mount Sinai have made an exciting discovery about how human cells make RNA, a molecule that carries important instructions inside our bodies.

Room-temperature stability aims to address significant supply chain challenges associated with some mRNA vaccines, including the dependence on ultra-low-temperature storage and complex delivery ...

The four nucleotides in mRNA form 64 unique codons, comprising 61 sense codons and 3 stop codons. Certain gene mutations can convert 18 of the 61 sense codons into stop codons. When this happens, the ...

This is known as a mixed vaccine series. The National Advisory Committee on Immunization (NACI) recommends an mRNA vaccine (Pfizer-BioNTech Comirnaty ® or Moderna Spikevax ®) should be offered for ...

Stop codons can sometimes be reinterpreted, allowing the cell to insert an amino acid rather than halting translation. This normally requires a specific signal in the mRNA that guides the ribosome ...

HIV/AIDS researchers in South Africa are reeling from the termination or suspension of grants from the US National Institutes of Health (NIH). Science1 reported that the cuts seem linked to a ...

The United States led the world in developing the technology that beat the COVID-19 pandemic. Action from lawmakers may leave that legacy—and a $70 billion market—behind.

Get Instant Summarized Text (Gist) A novel class of zwitterionic phospholipids, specifically DOPE-Cx, significantly enhances mRNA delivery by facilitating endosomal escape, a major challenge in ...