Noninvasive monitoring of immune responses is important for increasing the efficacy of cancer immunotherapy. Although several approaches exist, few methods directly report on T-cell activation. We ...

Quantitative 18F-FDG PET is increasingly being recognized as an important tool for diagnosis, determination of prognosis, and response monitoring in oncology. However, PET quantification with, for ...

Aptamers are small oligonucleotides that are selected to bind tightly and specifically to a target molecule. We sought to determine whether aptamers have potential for in vivo delivery of ...

In the tubules of the kidney, small proteins and polypeptides are reabsorbed after glomerular filtration. An important mechanism of reabsorption is uptake via megalin, a 660-kDa transmembrane ...

The Highlights Lecture, presented at the closing session of each SNMMI Annual Meeting, was originated and presented for more than 30 y by Henry N. Wagner, Jr., MD. Beginning in 2010, the duties of ...

Quantitative Analysis in Nuclear Medicine Imaging is an in-depth review of single-photon and PET nuclear medicine image reconstruction, correction, modeling, and analysis techniques, with a particular ...

329 Objectives Stimulant medications (methylphenidate and amphetamine) are the treatments of choice in ADHD and are believed to acutely compensate for a chronic dopamine (DA) deficit in this disorder.

Several translocator protein (TSPO) PET studies have shown increased glial cell density in Parkinson disease (PD); however, TSPO tracers are not able to differentiate between proinflammatory and ...

In PET studies of patients with Alzheimer's disease (AD) prominent hypometabolism can occur in brain-regions without major amyloid load. These "hypometabolism only" (HO)-areas may not be explained ...

International guidelines recommend salvage radiotherapy (sRT) as a curative treatment for men with biochemically recurrent prostate cancer after radical prostatectomy. Prostate-specific membrane ...

SPECT is a rapidly changing field, and the past several years have produced new developments in both hardware technology and image-processing algorithms. At the component level there have been ...

The goals of DICOM are to achieve compatibility and improve workflow efficiency between imaging systems and other information systems in health care. Every major vendor of diagnostic medical imaging ...