RNA vaccines train the immune system in a similar way to traditional vaccines, but they use a different strategy to get there ...

mRNA is synthesized by the enzyme RNA polymerase. This occurs by using the sequence of bases in a DNA strand to create a complementary mRNA strand. This pre-mRNA is then processed—spliced ...

She studies circular RNAs formed as a result of so-called molecular mistakes that occur when a strand of RNA—the ... They ...

Getting therapeutic drugs past the blood-brain barrier has long been a major challenge in treating brain diseases. Now, researchers have explored how cholesterol-modified heteroduplex oligonucleotides ...

Getting therapeutic drugs past the blood-brain barrier has long been one of medicine's most difficult challenges, limiting ...

Researchers at Tokyo University of Science have developed Chol-HDOs, which efficiently penetrate the brain, overcoming ...

This process repeats along the length of the mRNA strand until the ribosome runs into a stop codon, a special sequence of three nucleotides that signals the end of the protein-making instruction ...

Advancements in mRNA vaccine technology are reshaping medicine, addressing challenges and expanding applications from ...