Among the major classes of RNAs in the cell, tRNAs remain the most difficult to characterize via deep sequencing approaches, as tRNA structure and nucleotide modifications can each interfere with cDNA ...

The yeast RGG motif-containing RNA binding protein Scd6 and its human ortholog LSM14A regulate the translation of specific ...

A team of scientists led by the A*STAR Genome Institute of Singapore (A*STAR GIS) have released one of the world's largest ...

In a report released today, Terence Flynn from Morgan Stanley maintained a Hold rating on Moderna (MRNA – Research Report), with a price target of $32.00. The company’s shares closed yesterday ...

Key suits were filed by third party mRNA and lipid pioneers that, while not having any mRNA-based products on the market themselves, leveraged their patent portfolios claiming a share of the ...

RNA splicing is a modification of the nascent pre-messenger RNA (pre-mRNA) transcript in which introns are removed and exons are joined prior to translation. For many eukaryotic introns ...

O-GlcNAcylation in humans is mediated by a single essential enzyme, O-GlcNAc transferase (OGT ... these data indicate a role for SFSWAP as a global negative regulator of pre-mRNA splicing and positive ...

In this article, we are going to take a look at where Moderna, Inc. (NASDAQ:MRNA) stands against other stocks that Jim Cramer discusses. In a recent appearance on CNBC’s Squawk on the Street ...

While GPATCH1 detects the defective pre-mRNA, DHX35 removes it from the spliceosome, which is subsequently disassembled and made available for a new round of splicing. Credit: Paulina Fischer ...

The research findings by Professor Kim Bit-naeri's team clarify the process by which mRNA is delivered to cells from vaccines and is not degraded by enzymes, which can significantly enhance the ...

We have optimized the expression level of our full-length mRNA (K1.1c) as well as a smaller, truncated version (K1.1d) in HCC tumors in mice. Following encapsulation in two specifically designed ...