Researchers from the International Institute of Molecular and Cell Biology in Warsaw (IIMCB) have described a new mechanism ...

Although RNA is a single-stranded molecule, researchers soon ... in a cell can "read" all 61 codons in mRNA. The opposite end of the folded structure, which is the 3' end of the tRNA, binds ...

In particular, there is an area near the 5' end of the molecule that is known ... Begins After the Assembly of a Complex Structure The translation of mRNA begins with the formation of a complex ...

The popularity of mRNA-based therapeutics has surged over the past few years. To ensure the safety of these treatments, scientists need to analyze the characteristics of the manufactured molecules, ...

Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell makes a copy of DNA, called mRNA. Then, another molecule called a ribosome reads the mRNA, translating it ...

To add multiple polyA tails to the mRNA backbone and create the branched structure, the scientists used click chemistry, which is a set of reactions used for joining two molecular entities. Additional ...

Penn Engineers have modified lipid nanoparticles (LNPs)—the revolutionary technology behind the COVID-19 mRNA vaccines—to not only cross the blood-brain barrier (BBB) but also to target specific types ...

In DNA, two complementary strands of nucleotides pair up through hydrogen bonds between the bases (A with T and G with C) to form the iconic double helix structure ... The resulting RNA molecule, ...

More information: Alexander Simonis et al, Persistent epigenetic memory of SARS-CoV-2 mRNA vaccination in monocyte-derived macrophages, Molecular Systems Biology (2025). DOI: 10.1038/s44320-025 ...

rRNA molecules, along with ribosomal proteins, form the structure of the ribosomes and catalyze the ... undergoes several processing steps before becoming a mature mRNA molecule: After processing, the ...

RNA epigenetic modifications have uncovered as not only an intermediary structure between DNA and protein or an effector ...

Researchers have discovered that mRNA-based COVID-19 vaccines have a ... Cologne and is a principal investigator at the Center for Molecular Medicine Cologne (CMMC), and Dr Robert Hänsel-Hertsch ...