The Los Angeles Chargers head to the preseason finale with some key battles set to unfold. Jim Harbaugh’s Chargers have shown an ability to look past draft status and emphasize performance, which is something that could show up big again at final cuts. Here’s a look at a final 53-man roster before the preseason finale.

Chargers vs. 49ers game will air on CBS Los Angeles. It can also be streamed on NFL+ for subscribers. Streaming options for the game include the ESPN app, ESPN Unlimited and Fubo, which offers a free trial. The game will begin at 8:30 p.m. ET / 5:30 p.m. PT.

The San Francisco 49ers resume Week 3 of the 2025 NFL preseason hosting the Los Angeles Chargers tonight. Start time, where to watch, stream and NFL schedule.