Aminoacyl-tRNA synthetases (aaRSs) are ubiquitous enzymes that provide the critical link between the genetic code and protein biosynthesis. By precisely catalysing the attachment of amino acids to ...

Over the past 500 million years, nearly all evolutionary changes in octopuses and squids occurred in rapid bursts during the ...

The mRNA codon in the ribosomal A-site is recognized by aminoacyl-tRNA (aa-tRNA) in a ternary complex with elongation factor Tu (EF-Tu) and GTP. Here we report the 13 Å resolution three ...

To address the challenge of controlling protein activation in living animals for gain-of-function studies, researchers from ...

The researchers uncovered that an important group of molecules known as aminoacyl-tRNA synthetases -- which help in translating RNA into proteins -- can also interfere with the transcription of ...

For as long as living things have been building proteins based on the code carried by messenger RNA molecules, aminoacyl-tRNA synthetases have been there. These enzymes, AARSs for short, link transfer ...

Image-guided vacuum-assisted biopsy to assess pathologic complete response in breast cancer patients with exceptional response to neoadjuvant chemotherapy. This is an ASCO Meeting Abstract from the ...

Defects in tRNA biology, such as mutations in tRNA genes or aminoacyl-tRNA synthetases, can lead to various diseases, including: Understanding the mechanisms of tRNA-related diseases and the potential ...

today announced multiple presentations at the International Union of Biochemistry and Molecular Biology’s 13 th International Symposium of Aminoacyl-tRNA Synthetases (AARS 2023), which is ...