Over the past 500 million years, nearly all evolutionary changes in octopuses and squids occurred in rapid bursts during the ...

Over the past 500 million years, nearly all evolutionary changes in octopuses and squids occurred in rapid bursts during the emergence of new species ...

To address the challenge of controlling protein activation in living animals for gain-of-function studies, researchers from ...

Charles W. Carter, Jr., from the Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, relates molecular recognition used in genetic coding to structures of aminoacyl ...

In eukaryotes, a group of aminoacyl-tRNA synthetases evolved to form a complex thought to facilitate protein synthesis by efficiently providing charged tRNAs to the translating ribosome. The human ...

today announced multiple presentations at the International Union of Biochemistry and Molecular Biology’s 13 th International Symposium of Aminoacyl-tRNA Synthetases (AARS 2023), which is ...

In scientific perspectives, the data demonstrated that the catalytic sites of PARS1 (and potentially those of other aminoacyl‐tRNA synthetases) can be explored as an effective pharmacological target.

Credit: Herney Gómez / Pixabay. Tevard Biosciences and Vertex Pharmaceuticals have announced a four-year global research partnership to develop new tRNA-based therapies to treat Duchenne muscular ...

Rapid and accurate mRNA translation requires efficient codon-dependent delivery of the correct aminoacyl-tRNA (aa-tRNA) to the ribosomal A site. In mammals, this fidelity-determining reaction is ...

Glutaminyl-tRNA synthetase (GlnRS) is one of the two enzymes in this ... ASSD is an autoimmune condition characterized by the presence of autoantibodies targeting one of several aminoacyl t-RNA ...