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Machine learning methods are widely used in bioinformatics and computational and systems biology. Here, we review the development of machine learning methods for protein structure prediction, one of ...
In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be ...
Scientists have discovered how a key protein helps maintain strong connections between brain cells that are crucial for ...
A major scientific advance in protein modeling developed by Microsoft Research AI for Science, has been published in Science.
Artificial intelligence is now designing custom proteins in seconds—a process that once took years—paving the way for cures to diseases like cancer and antibiotic-resistant infections. Australian ...
Advancements in artificial intelligence (AI) are dramatically transforming the field of protein science, offering powerful ...
Given the amino-acid sequence or 3D structure of a protein, how much can we predict about its function using just a desktop computer? The recent explosive growth in the volume of sequence data and ...
Protein classification is a fundamental task in computational biology, aiding in function prediction and disease analysis. This study uniquely investigates the complementary role of secondary ...
Understanding the alkaline stability of quaternary ammonium (QA) cations tethered to polymer backbones in anion-exchange membranes (AEMs) is crucial to advance the long-term performance of ...
Significance The present crystal structure of phenylalanine hydroxylase (PAH) provides the 3D structure of the full-length human PAH, both unbound and complexed with the tetrahydrobiopterin (BH 4) ...
Possible tetramer-based quaternary structures for the alpha-crystallins and small heat-shock proteins. Exp Eye Res 1993; 56:729–32. Article CAS Google Scholar Carver JA, Aquilina JA, Truscott RJW .
In this work, we investigated the structure and dynamics of the wild-type bovine odorant-binding protein (wt-bOBP), which is a domain-swapped dimeric protein, and the triple mutant deswapped monomeric ...
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