Both Tabrizi and Yang think that knocking down MSH3 could stave off HD pathology. Tabrizi noted that MSH3 also modifies other run-on repeats, including those causing fragile X syndrome, myotonic ...

Scientists have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that has long been limited by the protective nature ...

Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering ...

The Mt. Sinai study could open the door to future therapies for Alzheimer’s, amyotrophic lateral sclerosis, brain cancer, and drug addiction.

This study demonstrates the critical role of Afadin on the generation and maintenance of complex cellular layers in the mouse retina. The data are solid, which provides important insights into how ...

This valuable work presents how PRDM16 plays a critical role during colloid plexus development, through regulating BMP signaling. Solid evidence supports the context-dependent gene regulatory ...

Jan. 28, 2025 — A new study shows that asymptomatic brain metastasis is more common in stage 4 breast cancer patients than previously believed. The study suggests ... Route of Entry for Semliki ...

BACKGROUND: Circular RNAs derived from both nuclear and mitochondrial genomes are identified in animal cells.

The Witcher 4 has now been officially revealed, with a new trailer confirming that the game will focus on Ciri as the main protagonist. This latest look does give us an idea as to the overall ...

Neuroscience is a multidisciplinary science that is concerned with the study of the structure and function of the nervous system. It encompasses the evolution, development, cellular and molecular ...

You might have heard of LCD TVs and monitors, you might know what LEDs are, but how they relate to new TVs isn’t especially clear. Alongside their best OLED TVs, Samsung, LG, Sony, TCL, Hisense ...

Concerns are rising that the US may no longer come to Europe's defence, which could force European countries - including the UK - to increase their military spending. Since the Russian full-scale ...