Key Takeaways Warren Buffett’s Berkshire Hathaway is set to hold its annual shareholder meeting and release its first-quarter financial results on Saturday.Investors will be watching closely to see what the "Oracle of Omaha" has to say amid economic uncertainty.

Investors often use Berkshire Hathaway's quarterly-filed Form 13Fs to track Warren Buffett's trading activity. Buffett has been a net seller of stocks for nine consecutive quarters, which has ballooned Berkshire's cash pile to $334 billion.

Warren Buffett has long complained that Berkshire Hathaway BRK.A BRK.B has become so huge that it’s difficult to find acquisitions that are both undervalued and large enough to make a material difference to the company’s bottom line.