Novel mechanisms that support cellular adhesion and tissue repair offer therapeutic potential
Northwestern Medicine investigators have discovered new mechanisms underlying cellular adhesion and repair, findings that ...
Unraveling structure and function relationships in synthetic cell receptors
Northwestern University researchers have identified structural features in engineered cell receptors that correlate with ...
Science Daily17h
Scientists identify a new cancer immunotherapy target: Dysfunctional B cells
Scientists have discovered a novel subset of cancer-fighting immune cells that reside outside of their normal neighborhood -- known as the tertiary lymphoid structure -- where they become ...
Dysfunctional B cells: A novel target for cancer immunotherapy and diagnostics
University of Pittsburgh School of Medicine and UPMC Hillman Cancer Center scientists have discovered a novel subset of ...
HIV protein switch may help virus squeeze into host cell nucleus
Supercomputer simulations have revealed how changes in the shape of the HIV-1 capsid protein may help the virus squeeze its ...
eLife6d
Genome Restructuring around Innate Immune Genes in Monocytes in Alcohol-associated Hepatitis
The manuscript addresses the 3D chromatin architecture in monocytes from patients with alcohol-associated hepatitis and its relationship to enhanced transcription of innate immune genes. While the ...