This important study advances our understanding of maladaptive innate immune training. The experimental evidence supporting the conclusions is convincing and the expert reviewers strongly endorse the ...

Emerging evidence indicates that dysfunctional mitophagy acts as a key pathogenic driver in the pathogenesis of DM and its associated complications. Natural small molecules are particularly attractive ...

A key role for ammonia in the pathogenesis of both HE and brain edema is now firmly supported by clinical and experimental data. Additional factors, such as infection, products of the necrotic ...

Progressive pulmonary fibrosis (PPF) presents a significant challenge ... Biomarker discovery for PPF has made significant new insights into disease pathogenesis and potential therapeutic targets.

Autopsy reports from previous Florida executions using etomidate revealed the presence of pulmonary edema—a condition where fluid floods the lungs, potentially causing a sensation akin to drowning.