In one of these patients, the voriconazole trough concentration was 9 mg/L, which is a toxic level. In the other ... In 3 other cases, tacrolimus toxicity was reported, with trough blood ...

tacrolimus (Prograf, 1–2 mg/kg twice daily to achieve a 'trough' serum level of 8–12 ng/ml; Table and Fig. 2). One died on day 73 of gastrointestinal bleeding. This monkey had become ...

The 12 h tacrolimus trough level was 48.1 ng/mL. On further questioning, it was found that due to confusion, the patient was inadvertently taking doses of the tacrolimus that were much higher than ...

CYP3A5 expressers require a 1.8-fold higher tacrolimus dose than non-expressers. A visual patient-tailored dosing chart, taking into consideration the child's weight, recent haematocrit level and ...

In the present study, donor CYP3A5 genotype was found to be strongly associated with the time to reach stable tacrolimus therapeutic trough concentrations and tacrolimus daily dose requirements in ...

SINGAPORE – The global sea-level rise due to climate change could be up to 90cm higher than earlier estimates by the end of the century, new research by NTU has found. The UN climate science ...

Turning our attention to the weekend and beyond, we see a cold trough of low pressure that ... the air aloft will continue to cool. Snow levels eventually will drop to the valley floor, mainly ...

Japan's internal affairs ministry on Wednesday presented a new plan to send officials from some prefectures to help other areas hit hard by a possible massive earthquake in the Nankai Trough off ...

the farm’s water trough will freeze over. When it does, Bradley cracks the ice and sits in the freezing water. She returned to the property this week with three medals from her second world ...

In this context, tacrolimus (TAC) (5 mg, twice daily) was added to the therapy, and the IRH level was reduced from Grade 3 to normal. Subsequently, TAC and MMF were gradually reduced and eventually ...

yahoo.com Objective To compare the efficacy of tacrolimus (TAC) and mycophenolate mofetil (MMF) for the initial therapy of lupus nephritis (LN). Study design This is an open randomised controlled ...