There are lots of different factors to consider, including genetics and your metabolism, when looking into the possible risks ...

rdb.aphp.fr Choosing the right dose of tacrolimus ‘adapted to each individual patient’ is a central question after transplantation. The pharmacokinetic behaviour of tacrolimus in paediatric patients ...

Metabolism often flies under the radar when designing a fat loss transformation program. A balanced 30-minute training session can boost your metabolism for up to 14 hours, which can be a game-changer ...

Using genetic markers to adjust initial doses of cyclosporine or tacrolimus may prove difficult, considering the variety of polymorphisms known to affect CYP3A4, CYP3A5, and MDR1. The current ...

Cytochrome P450 3A isoenzymes (CYP3A), mainly CYP3A4 and CYP3A5, are involved in tacrolimus metabolism. Several human studies have been conducted to identify endogenous biomarkers of CYP3A activity.

Interestingly, we note that some recipients of rapid tacrolimus metabolism must be switched to another immunosuppressive regiments for both economic and safety reasons. Hence, we wonder about the ...

Metabolism refers to the chemical reactions that occur within an organism to sustain life. The reactions are divided into two categories: catabolism (the breakdown of organic matter to produce ...

Src-family kinases (SFKs) are central regulators of both immune cell functionality and metabolism. The c-terminal Src-Kinase CSK is an inhibitor of SFKs. Acute kidney injury (AKI) is a disease in ...