[20,22,25] Lower tacrolimus disposition in young children might be related to an increased tacrolimus intestinal first pass metabolism resulting from higher CYP3A4 and CYP3A5 expression in the ...

The immunosuppressant drug tacrolimus may significantly improve relapse-free survival vs. mycophenolate mofetil for children with frequently relapsing nephrotic syndrome, according to study data.

This paper reviews the currently available evidence on the use of topical tacrolimus in atopic dermatitis and other conditions, as well as its safety profile and cost-effectiveness.

Tacrolimus is available in the form of a capsule, granules for oral suspension (to be mixed with liquid), an extended-release capsule and a tablet to be taken orally.

Findings on tacrolimus use in lung transplant patients, showing its effectiveness over cyclosporine in preventing chronic lung allograft dysfunction and improving survival.

Compared with the systemic calcineurin inhibitor standard cyclosporine, tacrolimus shows promise for numerous dermatologic conditions, whereas the literature on voclosporin is limited, according ...

Tacrolimus and cyclosporine A show similar efficacy in long-term survival and relapse reduction in AML post-transplant patients. No significant differences were found in leukemia-free survival ...