A genetic mutation and evolutionary trick fuels horses' exceptional athleticism, findings that may advance scientific ...

Researchers have pinpointed a genetic mutation and evolutionary process that appears to have optimized horses’ speed and ...

In the full study, conducted in collaboration with the Castiglione Lab at Vanderbilt University and partially funded by the ...

Horses have a rare genetic adaptation that helps improve athleticism. This evolutionary mechanism could improve human ...

It basically put a stop sign, called a stop codon, toward the beginning of the KEAP1 gene. Stop codons generally signal where a gene ends, so having one at the start would "break" the gene.

In preparing for their study, the researchers came across a premature stop codon in equine versions of the gene compared to other species. Located unusually early in the protein sequence ...

Consequently, the mutant protein is entirely different due to the deletion of the fourth nucleotide, and it is also shorter due to the appearance of a premature stop codon. This mutant protein ...

They also highlight how the recoding of a de novo stop codon – a strategy thought restricted to viruses – can facilitate adaptation in vertebrates. Long prized for their speed and endurance ...

The codons UAA, UAG, and UGA are the stop codons that signal the termination of translation. Figure 2 shows the 64 codon combinations and the amino acids or stop signals they specify. As ...

Each gene has usually two versions within the library: with and without stop codon. If you plan to make use of a vector containing C-terminal tags, select the version without stop codon. The MGC ...