Self-renewing hematopoietic stem cells created for transplantation Date: May 17, 2017 Source: Weill Cornell Medicine Summary: An innovative method to make an unlimited supply of healthy blood ...

Stem cells, which live in tube-like "crypts" deep in the gut lining, are vital to the renewal process, dividing and differentiating into different cell types that replace old cells.

Multipotent stem cells are cells that have the capacity to self-renew by dividing and to develop into multiple specialised cell types present in a specific tissue or organ. Most adult stem cells ...

"The dormancy is the prerequisite for this unique ability of stem cells," explains Andreas Trumpp, a stem cell expert at DKFZ and HI-STEM. The almost unlimited self-renewal capacity is considered a ...

“In alert mode,” Prof. Oostendorp explained, “the stem cells first influence the behavior of the tissue cells—which, in turn, impact on the stem cells, triggering the self-renewal step.” ...

To continuously grow precious stem cells in vitro, researchers must preserve their “stemness.” They often accomplish this by using feeder cells, such as mouse or human fibroblasts, that deliver ...

Stem cell scientists have discovered the gene GATA3 has a role in how blood stem cells renew themselves, a finding that advances the quest to expand these cells in the lab for clinical use in bone ...

The adult stem cells used in the study were isolated from a mixed population of satellite cells from the skeletal muscle of mice. Investigators genetically engineered the transplanted MusSC to ...

Stem cells function as a source of new cells to grow or replace specialised tissues. To perform this function, these cells must divide to renew themselves, while some of their descendants ...

This is an excerpt of the Health Rounds newsletter, where we present latest medical studies on Tuesdays and Thursdays. To ...

The delicate balance between cell death and regeneration is crucial for human health and longevity. Most mechanisms involved in programmed cell death (PCD) play a key role in normal tissue renewal ...

A team of researchers led by Andreas Trumpp now wanted to find out which molecular signals control the self-renewal ability. In their current analyses, they discovered in mice that dormant blood stem ...