The assembly of a bipolar microtubule-based spindle is crucial for the accurate and timely segregation of the chromosomes into the two daughter cells during mitosis. Three microtubule nucleation ...

Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper cell division. During ...

a cell type that is simple enough to be understandable and amenable to experimental modification. Recent projects have focused on spindle length instabiliity and self assembly of a bipolar spindle.