Starting at 10 weeks old, the mice were moved to a sleep fragmentation chamber, where a swipe bar swiped across their cages every 30 seconds during a six-hour stint each day, keeping the nocturnal ...

Sleep disorders may lead to structural brain changes, ... A 2025 review found that stress related sleep disturbances activate brain immune cells such as astrocytes and microglia.

As cases of sleep disorders such as insomnia and sleep apnea increase, health experts are raising serious concerns about the ...

Microglia interact with neurons to promote not just phagocytic removal of synapses (Paolicelli et al., 2011; Schafer et al., 2012) ... EEG 40 Hz Coherence Decreases in REM Sleep and Ketamine Model of ...

Microglia are important to brain function, and also seem to play a role in disease. ... Sleep Disorders. LIVING & WELL. Healthy Aging. Child Development. Teen Health. Strange & Offbeat .

In the developing brain, weak synapses are pruned away by microglia (resident phagocytic myeloid cells) through a process involving the neuronal expression of classic complement proteins such as ...

Microglia, the immune cells of the brain, have long been the underdogs of the glia world, passed over for other, flashier cousins, such as astrocytes. Although microglia are best known for being ...

Spatial Phenotypic Characterization of Microglia via CODEX Multiplexed Imaging Reveals Sub-Population-Level Relationships With Pathogenic Features in Alzheimer’s Disease Brains Bahareh Ajami ...

A new study finds that microglia with mutant TREM2 protein reduce brain circuit connections, promote inflammation and contribute to Alzheimer's pathology in other ways. A rare but potent genetic ...