Three Johns Hopkins experts discuss the potential of mRNA-powered therapeutics to produce lifesaving treatments and cures for ...

Acetylation is a chemical modification that can be placed on and removed from the cable drum like a plug, causing changes in gene expression ... "Our findings show that mRNA vaccines induce ...

When a gene is to be expressed, the base sequence of DNA is copied or transcribed into mRNA (messenger RNA). This process takes place in the nucleus and occurs in a series of stages. The two ...

This unique property facilitates membrane fusion-mediated endosomal escape, leading to improved mRNA expression in the liver compared to conventional phospholipids such as DSPC and DOPE.

In this article we give an overview of RNA-based HPV diagnostics and the role of E6/E7 mRNA detection as a predictive ... upregulation of E6 and E7 expression. High-risk HPV DNA is detected ...

We have optimized the expression level of our full-length mRNA (K1.1c) as well as a smaller, truncated version (K1.1d) in HCC tumors in mice. Following encapsulation in two specifically designed ...

The new proof of concept study published in ACS Nanoscience Au may be the first to show ... protein expressions to improve therapeutic outcomes. "Our work will have a huge impact on mRNA and ...

Ovarian cancer, a leading cause of death among gynecological malignancies, has a poor prognosis and low 5-year survival rate, necessitating new therapeutic strategies. CDK4/6 inhibitors show promise ...

Acetylation is a chemical modification that can be placed on and removed from the cable drum like a plug, causing changes in gene expression ... "Our findings show that mRNA vaccines induce ...

Acetylation is a chemical modification that can be placed on and removed from the cable drum like a plug, causing changes in gene expression without changing ... “Our findings show that mRNA vaccines ...