aDepartment of Pediatric Oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Collaborative Innovation Center for Cancer Medicine, Sun ...

Liver metastases from melanomas, sarcomas, and renal tumors are less frequent. Treatment and prognosis will depend on whether they are isolated or multiple, size and location, the presence or absence ...

Background: Soft tissue sarcoma (STS) typically originates in the muscles and is associated with a poor prognosis. Undifferentiated pleomorphic sarcoma (UPS) is the most commonly diagnosed subtype of ...

The FDA has granted accelerated approval to avutometinib (VS-6766) plus defactinib (VS-6063) for the treatment of adult patients with KRAS-mutated recurrent, low-grade serous ovarian cancer (LGSOC) ...

This is a valuable study describing how rhabdomyosarcoma fusion-oncogenes, VGLL2-NCOA2 and TEAD1-NCOA2, function at the genomic, transcriptional, and proteomic levels in multiple systems. The ...

What is also exciting is the novel drug combination that was identified may supersede existing treatment for soft tissue sarcomas," said Asst Prof Yang. This study marks a pivotal step toward ...

Natera has announced findings from a study evaluating its personalised tumour-informed molecular residual disease (MRD) test, Signatera, in individuals with soft tissue and bone sarcomas.

With over 70 distinct histologic subtypes, sarcomas are stated to be a heterogeneous group of rare cancers. Credit: Phongphan / Shutterstock. Natera has announced findings from a study evaluating its ...

Results of the study (Utilizing Circulating Tumor DNA to Monitor Sarcoma Treatment and Recurrence) were presented at the 2025 Society of Surgical Oncology (SSO) Annual Meeting in March.

More information: Sharon Pei Yi Chan et al, Functional combinatorial precision medicine for predicting and optimizing soft tissue sarcoma treatments, npj Precision Oncology (2025). DOI: 10.1038 ...