For STAT6, we completed IND-enabling studies for ... The decision to expand the Phase II program was to structure the hidradenitis suppurativa and atopic dermatitis trials with the necessary ...

Signal transducer and activator of transcription 6 (STAT6) is a member of the STAT family involved in the regulation of immune response and inflammation. The development of SH2 domain inhibitors ...

Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...

This was primarily due to increased expenses related to the investment in the STAT6 and TYK2 degrader programs, platform and discovery programs, as well as a rise in occupancy and related costs ...

The fireside chat will be webcast live and may be accessed via a link in the Investors section of the Nurix website. The archived webcast will be available for 30 days after the event. About Nurix ...

Stay informed in an emergency, set your local ABC radio station in the ABC listen app, and find the frequency on your battery-powered radio. Making sense of emergency warnings It doesn't matter ...

Anterior gradient 2 (AGR2) is a protein located in the endoplasmic reticulum involved in protein folding and when stressed, it is secreted into the extracellular space and it attracts monocytes, ...

The company develops STAT6, a Type 2 inflammation in allergic diseases; and TYK2, a treatment for inflammatory bowel disease, psoriasis, psoriatic arthritis, and lupus. The company was ...

Activation of an immune signaling molecule called STAT6 may lead to pulmonary hypertension (PH) in people with oxygen deprivation due to obstructive sleep apnea, according to a recent study in mice.