RNA vaccines train the immune system in a similar way to traditional vaccines, but they use a different strategy to get there ...

This normally requires a specific signal in the mRNA that guides the ribosome to override the stop ... Two proteins involved in reading stop codons (SBP2 and eEFSec) carry mutations unique to ...

Another company looking to initiate clinical trials with an epigenetic-editor-based treatment for hepatitis is nChroma Bio.

RNA is generally single-stranded, as DNA is transcribed by RNA polymerases into mRNA (messenger RNA), which is read by ribosomes to generate protein (translation). Biologically active RNAs ...

Researchers from the International Institute of Molecular and Cell Biology in Warsaw (IIMCB) have described a new mechanism ...

Once injected, these mRNA molecules enter the cytoplasm of host cells, where ribosomes translate them into antigenic proteins. These proteins are then displayed on the cell surface, triggering ...

Furthering its goal to grow the reach of its mRNA vaccines and guard against future pandemics, Moderna cleared a key regulatory hurdle at its flagship production plant in the United Kingdom.

Cellular factors that regulate the delivery and stability of mRNA vaccines in the body were revealed, proposing a new paradigm for mRNA therapeutics Date: April 3, 2025 ...

Researchers have discovered that mRNA-based COVID-19 vaccines have a ... The observed epigenetic changes led to increased 'reading' of pro-inflammatory genes, which in turn led to the production ...

The world was desperate for scientific solutions. PREMIUM Vials of Covid-19 mRNA vaccines. (Reuters File Photo) I remember vividly the wave of hope that arrived in November 2020 when Pfizer ...