First-in-class approach to targeting mitochondrial DNA polymerase (POLG) with disease modifying potential across mitochondrial DNA depletion syndromes ...

Single-Molecule Footprinting reveals that RNA polymerase II (Pol II) occupancy is infrequent at mouse promoters. This results ...

The University of Hong Kong has patented RNA polymerase β subunit/RNA polymerase sigma factor RpoD (bacterial) interaction inhibitors reported to be useful for the treatment of gram-positive bacterial ...

Primrose Bio announced a new product to improve the manufacturing on long-template mRNA vaccines. 1 The Prima RNApols ExTend ...

Corp. and St. Jude Children’s Research Hospital Inc. have jointly patented compounds acting as caseinolytic protease P (ClpP) (bacterial) activators and RNA polymerase (bacterial) inhibitors and their ...

Primrose Bio, Inc. ("Primrose"), a company developing proprietary therapeutic manufacturing technologies, announces the ...

Two types of COVID-19 tests, the rapid antigen test and the polymerase chain reaction (PCR) test, are available in the United States. The PCR typically relies on lab testing and is still considered ...

Using an unbiased approach, this important study discovered a role of Ezh2 in the differentiation of granule neuron precursors, the cell of origin for Shh group of medulloblastoma. Furthermore, the ...

With the long-term goal of creating living cells from non-living components, scientists in the field of synthetic biology work with RNA origami. This tool uses the multifunctionality of the natural ...