Ribonucleic Acid (RNA) polymerase is an intermediary enzyme responsible for processing gene sequences into RNA-based genetic material that can be utilized in protein synthesis. In this article, we ...

By tethering RNA polymerase with the coupling transcription factor NusG or its paralog or version, RfaH, which threads the ...

Transcription termination is one of the least-understood processes in gene expression. However, recent studies have revealed common themes and principles between models of RNA polymerase II (Pol ...

With the long-term goal of creating living cells from non-living components, scientists in the field of synthetic biology ...

Their simulation of the initiation phase of transcription in bacterial RNA polymerase showed a three-step process. It begins when the RNA polymerase binds with transcription promoting regions of DNA.

From a cell's point of view, without RNA polymerase DNA is just an oversized, unreadable data storage system. RNA polymerase is responsible for the process of transcription, where the information ...

Image Credit: tigerder/Shutterstock RNA-dependent RNA polymerase (RdRp) is a key enzyme for SARS-CoV-2 genomic replication and transcription and, thus, for viral replication.

Scientists have recently uncovered the mechanisms of how RNA polymerase II performs intrinsic cleavage reaction to proofread RNA transcriptions, shedding light on how misregulation of accurate ...

The studies, each of which uses different methodologies, find RNA polymerase II boarding both upstream and downstream of start sites, and generating antisense RNA at many places across the genome.

CleanScribe RNA Polymerase provides researchers with a simple way to significantly reduce dsRNA in their IVT without compromising other important mRNA quality attributes.

The researchers found that using a drug to inhibit RNA Polymerase 1 (Pol 1) - the enzyme responsible for human ribosomal RNA (rRNA) transcription - triggered a unique stress response that rewires ...

A breakthrough assay is advancing how researchers observe gene expression in real time. Named QRIVTA (quantitative real-time ...