This study identifies 53BP1 as an interaction partner of GMCL1 (a likely CUL3 substrate receptor). The study seeks to link this finding to regulation of the mitotic surveillance pathway and paclitaxel ...

Somatic hypermutation (SHM) of immunoglobulin variable (V) regions modulates antibody-antigen affinity is initiated by activation-induced cytidine deaminase (AID) on single-stranded DNA (ssDNA).

Non-coding RNAs (ncRNAs) are RNA molecules that do not encode proteins but are involved in dynamic cellular regulatory ...

Through international collaboration, researchers at KAIST have revealed that RNA editing plays a crucial role in regulating neuroinflammation, a key pathology of Parkinson's disease. The paper is ...

When RNA molecules are synthesized by cells — a critical process in the creation of proteins and other cellular functions — they typically undergo a series of “folding” events that determine their ...

This revolution is being powered by RNA technology — and Canada is uniquely positioned to lead it. While the swift development of COVID-19 vaccines appeared to be a sudden scientific triumph ...

The number of people suffering from osteoarthritis is expected to top 1 billion by 2050. The biggest risk factor for the prevalent, often painful, chronic joint disease is aging. And like aging ...

This study develops tools to measure LRRK2 activity and expression in immune cells relevant to Crohn’s disease, revealing ...

This discount is shown at checkout, if applicable. A start-up targeting regulatory RNA is one step closer to getting a drug candidate into human trials with the help of $65 million in series A ...

United Kingdom Genomics Market: The UK’s genomics market is forecasted to reach USD 7.5 billion by 2032, growing at a CAGR of 20.4% from 2022 to 2032. This represents an absolute dollar opportunity of ...