Previous studies have shown that α9-integrin expression and activation in mature dorsal root ganglion neurons enable the regeneration of injured axons within the spinal cord. However, tissue ...

Nat Clin Pract Oncol. 2007;4(10):556-557. Although strategies for imaging angiogenesis are in the development phase, they have the potential to accelerate oncology drug development. Direct ...

As discussed below, anti-integrin therapies may represent such a novel anti-invasive therapy.

As the TH binding site upon the integrin is at close proximity to the well-defined RGD binding site, linear and cyclic RGD were included as a reference. Binding energy was calculated for each receptor ...

Peptides such as Arg-Gly-Asp (RGD), which can mimic integrin-binding sequences on naturally occurring proteins, can be incorporated within polymeric biomaterials to study, for instance, the ...

The initiation of integrin‐mediated adhesion consists of two main steps. The first is the initial activation of integrins, which enables them to bind ligand. The second is the generation of force on ...