While a comprehensive cure-all to these neurological conditions is unlikely, scientists are making headway into understanding their fundamental characteristics with the hope of preventing or ...

Cell crowding causes high-grade breast cancer cells to become more invasive by activating a molecular switch that causes the cells to shrink and spread.

New research reveals that neurons can switch their migration strategy depending on whether they move on flat surfaces or through tight, crowded spaces.

Here, we discover lysophospholipids as endogenous pannexin activators, using activity-guided fractionation of mouse tissue extracts combined with untargeted metabolomics and electrophysiology. We show ...

A research team from the Qingdao Institute of Bioenergy and Bioprocess Technology of the Chinese Academy of Sciences, along with collaborators, has introduced a novel membrane design that mimics ...

These cells carry a lot of ion channels in their plasma membranes ... is found underneath the plasma membrane. This enzyme was discovered many years ago. When cells are soft and deformable ...

Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...

Molecular dynamics (MD) simulations of membrane proteins cover a wide range of applications and specialized techniques. These techniques accurately combine two challenges into one: properly capturing ...

Initiator caspases activate executioner caspases to carry out mass protein breakdown throughout the cell. In extrinsic and intrinsic apoptosis, this destruction induces the formation of apoptotic ...

The plasma membrane of vascular smooth muscle (SMC ... Finally, we will provide the audience with a detailed picture of the unique lipid-protein interactions that confer vascular Kir2 channels the ...

Integral membrane proteins such as receptors and ion channels span the membrane. Peripheral membrane proteins, for example some signalling proteins, are tethered by an anchor, via a fatty acid ...