The FDA has cleared the investigational new drug (IND) application of GLIX1, a first-in-class small molecule targeting DNA repair vulnerabilities, offering a potential therapy for glioblastoma. 1 With ...

Revisiting Phase 1 of the MCU in 2025 makes the mega-franchise's early days seem quite different in hindsight.

This marks Phase 1 Equity's fifth practice added in 2025, its 14 th doctor to join the platform and brings total locations to 22.

About CLARICO CLARICO is a Phase 1/2a first-in-human, multisite, 2-part interventional study to evaluate the safety, tolerability, and the effect on clinical outcomes of OpCT-001 in up to ...

Pfizer Inc. has initiated a new clinical study titled A Phase 1, Randomized, Double Blind, Sponsor-Open, Placebo-Controlled, Single Dose Escalation Study to Evaluate the Safety, Tolerability, and ...

ART-101, a novel PSMA-targeting small molecule, received FDA IND clearance for mCRPC treatment, enabling a phase 1 trial launch. Preclinical studies show ART-101 has higher tumor uptake and lower ...

The researchers enrolled 20 participants into their phase 1 between March 15 and March 23, 2023. The participants were healthy Japanese men between the ages of 19 and 51. All of them were included in ...

Schrödinger announces encouraging initial clinical data from its ongoing Phase 1 dose-escalation study of SGR-1505.

Kymera's KT-621 shows promising STAT6 degradation in Phase 1 trials, with favorable safety and planned further studies in 2025. Quiver AI Summary Kymera Therapeutics announced encouraging results ...