In order to advance a hit molecule into a therapeutic lead, many of the compounds attributes must be optimized including solubility, potency, pharmacokinetics, toxicity, etc. These development ...

At each stage of the validation process, results are immediately fed back into the predictor for full optimization of the predictive feedback loop. Lead peptides progress to optimization ...

This breakthrough in cyclic peptide design for β-catenin ... structure prediction and target validation to hit discovery and lead optimization. In addition, the platform offers an interactive ...

Acquisition adds potential novel oral peptide IL23R inhibitor for psoriasis as well as a peptide synthesis, screening and optimization ... Nimble's lead asset is an investigational oral peptide ...

Nimble's lead asset ... oral peptide IL23R inhibitor in preclinical development for the treatment of psoriasis. Additionally, Nimble's peptide synthesis, screening, and optimization platform ...