Apoptosis is dependent on caspase activation, whereas the caspase-independent necrotic signaling pathway remains largely ... in a highly sensitive fibrosarcoma cell line, Fas triggers cell death ...

Figure 2 Metabolic pathways affecting ferroptosis ... In fact, knocking out NADPH increases the sensitivity of fibrosarcoma HT1080 cells to ferroptosis (Shimada et al., 2016a). In the presence of ...

Stimulation of RHAMM by HA has also been shown to activate less reported pathways such as β-catenin to up-regulate the expression of the oncogene c-MYC which promoted tumour growth and proliferation ...

Digital technologies and AI are disrupting the way people live, work, and learn. At the same time, education systems need to become both a rapid producer and an avid consumer of digital and data ...

MANILA, Philippines — A bill to allow graduating junior high school students to pick alternative education pathways has been approved on third and final reading by the House of Representatives ...

Overall, digital pathways in education and skills development can be seen as the interplay of two dimensions: (1) depth of digital transitions, the extent to which public policy efforts take a ...

This important study demonstrates the potential of synthetic gene circuits to detect and target aberrant RAS activity in cancer cell lines. The circuit design is novel and the evidence supporting the ...

In 2025, Canada will unveil four new permanent residency pathways aimed at tackling labor shortages and creating more opportunities for foreign nationals. These initiatives include the Enhanced ...

SHENZHEN, China, Jan. 24, 2025 /PRNewswire/ -- From January 13 to 16, Dr. Huiming Li, Deputy General Manager of Kexing Biopharm New Drug Research Center, attended the 17th Biotech Showcase ...

The National Academies of Sciences, Engineering, and Medicine are private, nonprofit institutions that provide expert advice on some of the most pressing challenges facing the nation and world. Our ...