The Research Ireland funding spans a four-year period and will support researchers and provide resources to establish their ...

Researchers have found that lack of a specific gene can interrupt neural tube closure. Researchers at the University of Colorado School of Medicine have found that lack of a specific gene ...

Wallingford, J.B. (2005) Neural Tube Closure and Neural Tube Defects Studies in Animal Models Reveal Known Knowns and Known Unknowns. American Journal of Medical Genetics Part C Seminars in Medical ...

Interestingly, the researchers found that the mice that had lost their tails showed a greater prevalence of spina bifida, a birth defect that affects the neural tube, an embryonic structure that ...

The following is a summary of “Maternal metabolism influences neural tube closure,” published in the September 2023 issue of Endocrinology and Metabolism by Keuls, et al. Alterations in the ...

NTDs are severe congenital malformations that result from failure of neural tube closure by the 28th day of gestation. The neural tube forms the early brain and spine.

The US Food and Drug Administration (FDA) mandated folic acid fortification of all enriched cereal grains in 1996, and this regulation resulted in a reduction of neural tube defect (NTD ...

Defective neural tube closure leads to neural tube defects which are some of the most common human birth defects. While the intrinsic morphogenetic events shaping the neuroepithelium have been studied ...

Neural-tube defects are considered to arise from a complex relationship between genomic and environmental factors, including maternal diabetes, hyperthermia, anticonvulsant agents, obesity, and ...

We achieved neural tube closure with an alternative model combining mesoderm expansion, nonneural ectoderm expansion, and neural plate adhesion to the notochord.

Objectives The association between ambient heat and neural tube defects has received limited attention, despite imminent climate warming this century. We sought to determine the relationship between ...

Defects in the posterior portion of the neural tube are referred to as meningomyeloceles (spina bifida), while the more anterior defects are differentiated as anencephaly, encephalocele, or ...