College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, P. R. China Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention ...

STONY BROOK, NY / ACCESS Newswire / March 26, 2025 / Applied DNA Sciences ... also known as H5 bird flu, highly pathogenic avian influenza, or H5N1 (collectively "H5 bird flu").

According to a study by the Manchester Fungal Infection Group, in 2022, approximately 6.5 million people were infected by a pathogenic fungus ... Ribonucleic acid (RNA) plays a central role in the ...

Type I Interferonopathy-associated variants of ARF1 disrupt retrograde transport of STING. Application of STING inhibitors reduce auto-inflammation of patient cells in vitro. ARF1 variants R99C and ...

a cytosolic DNA ... STING. STING serves as a signaling platform for the recruitment and activation of TBK1, IRF3 and NF-κB for the transcriptional activation of type I interferons. type I interferon, ...

Image: NIRBA will engage scientists and clinicians from leading institutions like NUS, A*STAR, NTU, and Duke-NUS Medical School, to build strategic research capabilities in RNA biology and ...

Department of Oral and Maxillofacial Surgery, The Affiliated Stomatological Hospital, Nanjing Medical University; State Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral ...

In Mavs-knockout mice, Chen noted that cells were “totally defective in immune defense against RNA viruses ... its place as the elusive cytosolic DNA sensor to complete the cGAS-cGAMP-STING pathway.

In this study, we foung that licorice extract inhibited the HT-DNA-induced activation of the cGAS-STING pathway in BMDMs but did not affect the activation of the RIG-I-MAVS pathway triggered by poly ...