Mammary organoids derived from mouse embryonic stem cells could offer clues into mammary gland developmental origins and help researchers study breast cancer. “When we use embryonic stem cells, they ...

Where the research has really made a difference is with stem cells. Because Dolly came from an adult sheep’s mammary cell, scientists learned they could change a cell’s gene expression when ...

Several lines of evidence suggest this pathway regulates mammary stem cell dynamics in normal mammary epithelial homeostasis. We are particularly interested in how alternative “noncanonical” modes of ...

Professor Jane Visvader and Associate Professor Shom Goel are recipients of the 2025 Academy honorific awards for their work ...

and human mammary epithelial cell lines for the study of breast cancer, three dimensional culture, and carcinogen screening. Its human cell culture products also consists of adult stem cells and ...

we study the communication between stem cells and their niche (e.g. neighbor cells, ECM) in multiple tissues including the intestine, mammary, skeletal muscle, and the hematopoietic system. Pekka is a ...

and Li, Y. Estrogen receptor positivity in mammary tumors of Wnt-1 transgenic mice is influenced by collaborating oncogenic mutations. Oncogene 24, 4220-4231 (2005). PMID: 15824740. Li, Y. and Rosen, ...