Perhaps the most compelling reason to revisit this question of MYC protein expression and localization in prostate cancer is the fact that no prior studies of MYC immunohistochemical staining in ...

In healthy cells, the MYC protein is critical to the transcription process, where genetic information is converted from DNA to RNA and, eventually, into proteins. But, in cancer cells, MYC becomes ...

The growth protein, MYC, was consistently found with RBM42, which spurs MYC production, in human pancreatic tumors. Above, microscopy for MYC (red) and RBM42 (green) in a representative pancreatic ...

Myc proteins play an important role when cells become cancerous. Researchers have studied just how they do this. They might thus open up ways to develop new therapies. Most human tumours have one ...

However, the reason for high c-Myc protein levels in most cases is unknown. We examined whether aberrant protein stabilization could be a mechanism of c-Myc overexpression in leukemia cell lines ...

Researchers have found that MYC protein may affect circadian rhythm and metabolism by promiscuously binding to promoter regions in key genes for maintaining these daily cycles. Myc is a cancer ...

To enable this, numerous mechanisms come into play, and one of them involves a protein called MYC, which activates certain genes on the cancer cell's DNA strand, causing the cancer cell to grow ...

The gene, known as Myc, has long been a target but was considered “undruggable” – so the team instead shut down a protein that it interacts with, shrinking tumors in a matter of days.

The protein produced by the MYC oncogene is a well-known foe in the oncology world. Its presence is associated with treatment-resistant cancer cells, which grow uncontrollably and evade the immune ...

MYC proteins are important regulators of cancer cell growth, proliferation and metabolism through their ability to increase the expression of proteins involved in these processes. Deregulation of ...

Ovarian cancer cells are "addicted" to a family of proteins produced by the notorious oncogene, MYC, and blocking these Myc proteins halts cell proliferation in the deadliest cancer of the female ...

Jess Thomson is a Newsweek Science Reporter based in London UK. Her focus is reporting on science, technology and healthcare. She has covered weird animal behavior, space news and the impacts of ...