Inhibiting RMB42 disrupted production of Myc proteins in pancreatic cancer cells. This approach could curtail the growth of several cancer types. A review paper published last year in European ...

Colorectal cancer is the third most diagnosed type of cancer worldwide. Up to 80% of the cases are related to environmental ...

What additional lessons can be learned? Is MYC stability altered at specific subcellular locales, or when in partnership with certain DNA, RNA or protein molecules, or as a mechanism to regulate ...

University of Pennsylvania researchers have developed a powerful new investigative tool to reveal how proteins work inside ...

UTR Therapeutics Inc. has submitted an IND application to the FDA for UTRxM1-18, a novel therapeutic approach for targeting c-MYC-driven cancers. Pending approval, a first-in-human phase I trial is ...

The mitochondrial unfolded protein response (UPR mt ... They also identified c-Myc as a key factor in the activation of UPR mt —overexpression of c-Myc significantly increased the expression ...

Burkitt lymphoma, a cancer that impacts a subset of immune cells called B cells, develops most often in children and young adults.  Patients with Burk | Cancer ...