Researchers have identified key immunological markers associated with mortality in hospitalised people living with HIV/AIDS.

Understanding the immune system is fundamental to advancing biomedical research, especially in areas such as cancer, autoimmune diseases, and infectious diseases. Mouse models play a pivotal role in ...

State Key Laboratory of Fine Chemicals, Frontiers Science Center for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian 116024, China State Key Laboratory of Fine ...

Multiplex cytokine analysis (Luminex xMAP) was used to measure serum levels of several ... IFN-α and GM-CSF did not meet the detection standards. ProcartaPlex™ assays use a sandwich enzyme-linked ...

allowing simultaneous quantitation of all protein targets with a Luminex instrument. The targets analyzed are listed below: Cytokines: G-CSF, GM-CSF, IFN alpha, IFN gamma, IL-1 alpha, IL-1 beta, IL-2, ...

Figure 1. (Left) examples of flexible VaxArray microarray-based assay designs, with 5’CapQ assay schematic highlighted, (Center) a schematic of a single VaxArray microarray slide with 16 ...

Roche has given two early-phase bispecifics the heave-ho, ending work on a HER2xCD3 prospect and an IL-15 candidate it picked up from Xencor. The drugmaker removed (PDF) the molecules from its ...

The levels of inflammatory plaque cytokines (MCP-1, IL-8, IFN-γ, IL-10, IL-1β, IL-6, PDGF-AA, PDGF-AB/BB, TNF-α, VEGF) were measured in tissue homogenates using a customized 10-plex Luminex assay.

Cytokines are proteins, peptides or glycoproteins secreted by lymphocytes and monocytes that regulate immune responses, haematopoiesis and lymphocyte development. Cytokines include interleukins ...