Mar. 13, 2025 — A study shows that high-grade glioma tumor cells harboring DNA alterations in the gene PDGFRA responded to the drug avapritinib, which is already approved by the United States ...

The histology is characteristic; lobulated masses of acini or lobules are densely packed together with little intervening stroma. The basement membrane is intact. Despite abundant proliferative ...

This can be due to a variety of reasons, including tumor size, stage, and location. Although an unresectable cancer can technically be any stage, it is usually stage III or IV. Surgery often offers ...