P enn Engineers have cooked up a new way to improve mRNA delivery, developing an optimal "recipe" for ionizable lipids—key ingredients in lipid nanoparticles (LNPs), the molecules behind the ...

Advancements in mRNA vaccine technology are reshaping medicine, addressing challenges and expanding applications from ...

When formulating mRNA into lipid nanoparticles (LNP), various copy numbers of mRNA are encapsulated, leading to a distribution of mRNA loading levels within the LNPs. It is unclear whether the mRNA ...

Engineered functionalized phospholipids hold great promise for developing lipid nanoparticles (LNPs) used in mRNA vaccines, cancer treatment, protein replacement therapy, and more. The derivative ...

such as direct injection of naked mRNA, lipid-based carriers, polymers, and protein derivatives. Those COVID vaccines that have experienced success are based around lipid nanoparticle delivery.

the precious mRNA payload is encapsulated in lipid nanoparticles. Recent elegant cryogenic-transmission electron microscopy [Biophys J 120, 2766 (2021)] reveals that these lipid nanoparticles take the ...

As we previously discussed, beginning in 2022, a series of patent infringement lawsuits were filed against Moderna and collaborators ...

Enoch Toh is a junior pursuing a Bachelor of Science in Molecular and Cellular Biology and Computer Science (CS). He is a ...

Following encapsulation in two specifically designed Lipid Nanoparticles, the resulting K1.1c-mRNA-LNP and K1.1d-mRNA-LNP were efficiently delivered to orthotopic engrafted HCC tumors in mice in a ...

The global lipid nanoparticles market, valued at US$ 820.51 million in 2023, is projected to experience significant growth, with an expected market valuation of US$ 2,387.98 million by 2032. This ...