Key experiments using an influenza DNA-LNP vaccine model demonstrated robust antibody and T cell immunity, lasting over a year in animal models. Additionally, a single shot of SARS-CoV-2 spike DNA ...

where they observed strong T cell and antibody responses that persisted into the memory phase. Finally, the team examined whether DNA-LNP vaccines could be protective in a live SARS-CoV-2 ...

The LNP-mRNA modality is a novel approach that ... Immunogenicity testing focuses on detecting small amounts of antidrug antibodies, so assay sensitivity needs to be carefully determined.

In contrast, polyethylene glycol (PEG)-lipid standards, commonly used in current LNP formulations, elicited a strong and boosted antibody response. Anti-PEG antibodies have been implicated as a ...

a pioneering technology provider specializing in mRNA and lipid nanoparticle (LNP) technologies. This collaboration seeks to revolutionize the discovery and development of therapeutic antibodies ...