A knockout mouse is a laboratory mouse in which one or more genes have been turned off or "knocked out." To create a knockout mouse, scientists genetically engineer the animal by disrupting a gene ...

Now a team has identified dozens of these genetic mutations in a screen of gene-targeted 'knockout' mice. Albinism is the best-known of a group of rare genetic disorders that can affect both eyes ...

New Joslin Diabetes Center study links brain insulin signaling, type 2 diabetes, and Alzheimer’s, revealing targets for ...

(Getty Images) The University of California, Davis, has been awarded just over $12 million from the National Institutes of Health under the third and final five-year phase of the Knockout Mouse ...

Collaborating with study co-authors Zachi Horn, a former postdoc in the Hatten lab, and with assistance from Shiaoching Gong, of Weill Cornell Medicine, Hanzel spent two years creating a knockout ...

JONATHAN LAMBERT, BYLINE: Neuroscientist Li Zhang has anesthetized a lot of mice for his research. Several years ago, as he brought these knocked-out mice back to their cages, he started noticing ...

or sometimes by switching off the gene altogether to see what happens if it doesn’t work (these are called knockout mice, and they’re a staple of medical lab research). In 2013, researchers in ...

RASCOE: So let's talk about the study. You and your colleagues temporarily knocked out mice with some medication or blocked their airways with a non-toxic ball. You noticed that the mice that were ...

The National Institutes of Health (NIH), announced the selection of the hospital's research institute for the Knockout Mouse Project (KOMP) on September 7, 2006. The $50 million initiative funded ...