May 8, 2025 — MicroRNA-27a has been shown to stimulate both the wingless-type integration site family, or Wnt signaling, and the bone morphogenetic protein pathways to actively promote bone ...

Bone is a mineralized connective tissue from which bones, the main component of the vertebrate skeleton, are formed. Bone tissue is composed of cells, namely osteoblasts, osteoclasts and ...

Bone metastases are cancers that have spread (metastasized) from other tissues in the body through the blood or lymphatic systems to the bone marrow. Bone metastases form the main type of bone ...

The status has been given to the B7-H3-targeted drug as a treatment for late-line relapsed or refractory osteosarcoma, a rare form of bone cancer with no FDA-approved treatments. The coveted ...

Jan. 28, 2025 — Researchers have combined injections of a novel hydrogel with systemic osteoporosis drugs in rats, achieving rapid local increases in bone density. The results offer hope for ...

One class of drugs that is frequently used in a nebulized form is the opioids. The mechanism of action of nebulized opioids is uncertain, but it is thought that the opioids either act on receptors ...

While we often focus on heart health or weight when we talk about sedentary habits, bones are also seriously affected by prolonged inactivity. Bone is a living tissue, and like muscles, it needs ...

These innermost flight feathers of the wing are attached to the elongated humerus bone in the upper arm. Birds evolved from small feathered dinosaurs, which lacked tertials. The discovery of them in ...

Notably, TTRL boosts the pass@1 performance of Qwen-2.5-Math-7B by approximately 159% on the AIME 2024 with only unlabeled test data. Furthermore, although TTRL is only supervised by the Maj@N metric, ...

23.7 45.3 (21.6) - CH / 800 m / tf / 2 bt 7 / Z Zuriman / Slow canter site (R.B.) (CH) / Swimming ...