C&EN17d
Proline cis/trans Conformational Selection Controls 14–3–3 Binding
Biophysical studies of a 21-residue phosphorylated PRLR fragment using isothermal titration calorimetry (ITC) and NMR spectroscopy show an interaction with a kinetic phase on the minute time scale. In ...
Frontiers19d
Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics
Together, recent advances in modern microscopy and improved genetically encoded calcium indicators (GECIs) have revolutionized systems neuroscience by allowing chronic simultaneous optical recording ...
Frontiers19d
A Pan-Pneumovirus vaccine based on immunodominant epitopes of the fusion protein
Respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) are two leading causes of severe respiratory infections in children, the elderly, and immunocompromised patients. The fusion (F) ...
Cancer Research18d
OBI-992, a Novel TROP2-Targeted Antibody–Drug Conjugate, Demonstrates Antitumor Activity in Multiple Cancer Models
Briefly, the anti-TROP2 antibody R4702 and human IgG1 isotype control (BE0297, BioXcell) in conjugation buffer (50 mmol/L histidine, 20 mmol/L ethylenediaminetetraacetic acid, pH 7.0) were treated ...
C&EN16d
Thiol, His–His Motif, and the Battle over Cu(II) in the Relationship of CopM Metallophore and OprC Outer Membrane Protein
Faculty of Chemistry, University of Wroclaw, 50-383 Wroclaw, Poland ...