SOUTH SAN FRANCISCO, Calif., May 08, 2025 (GLOBE NEWSWIRE) -- Assembly Biosciences, Inc. (Nasdaq: ASMB), a biotechnology company developing innovative therapeutics targeting serious viral diseases, ...

Pharmaceutical Technology Co. Ltd. has described Werner syndrome ATP-dependent helicase (WRN; RECQ3; RECQL2) inhibitors reported to be useful for the treatment of cancer.

For patients with cancers harboring certain genetic defects, the first-in-class targeted therapy RO7589831, which targets the DNA repair enzyme Werner helicase, demonstrated early signals of efficacy ...

RO7589831, a new drug from Roche, is first in a new class of drugs called Werner helicase inhibitors. Drug works similarly to ...

Provided herein are novel spirocyclic WRN helicase inhibitors, pharmaceutical compositions, use of such compounds in treating cancer, and processes for preparing such compounds. Werner syndrome dsDNA ...

helicase-primase inhibitor (HPI), could redefine the treatment landscape for recurrent genital herpes (RGH) through monthly or weekly oral dosing. With promising pharmacokinetics (PK), strong tissue ...