Here, we use a pH-reporter system and find that nerve injury triggers a reorganization of excitatory synapses that is influenced by the accumulation of the ganglioside GT1b at afferent terminals. GT1b ...

Narrow-moat Daiichi Sankyo is a Japanese drugmaker with a global footprint and cutting-edge development platform for antibody drug conjugates. As an established pharmaceutical company with a long ...

Our team of proven drug developers is advancing an antibody-drug conjugate with our proprietary linker technology, a T-cell engager with wide therapeutic window, and a multi-functional checkpoint ...

Granite Bio is ready to rock 'n' roll, unveiling with $100 million and hopes of shaping new antibody treatments targeting several autoimmune diseases. The funding consists of a $30 million series ...

Full results from the trial evaluating Akeso’s first-in-class PD-1/VEGF bispecific antibody are expected to be presented later this year at a medical conference. 1 "The interim analysis results from ...

Like the name says, antisperm antibodies fight sperm. It happens when the immune system mistakenly targets sperm in a man’s semen as an invader and damages or kills it. Antisperm antibodies aren ...

Molecular parameters governing antibody FcγR signaling and effector functions in the context of HIV envelope. Cell Reports , 2025; 44 (4): 115331 DOI: 10.1016/j.celrep.2025.115331 Cite This Page : ...

“Many of the most promising new therapies are antibodies, which cannot efficiently reach the brain without a shuttle to get them across the [blood brain barrier],” Austin added. “This ...

Bispecific antibodies enhance immune response by targeting myeloma and immune cells, showing high efficacy in multiple myeloma treatment. Tecvvayli, Talvey, and Elrexfio demonstrate significant ...

Harrison's plasma contained the rare antibody Anti-D, also known as Rhesus D antibody, which is used to make the medication given to mothers whose blood is at risk of attacking their fetuses.