The recent findings of Waldo et al. 1 demonstrate that the fusion of the green fluorescent protein (GFP) to insoluble proteins dramatically reduces its folding ability in prokaryotic cells.

Hematopoietic stem cells (HSCs) can differentiate into any blood cell. However, as HSCs age, they are more likely to ...

I’ve been a discovery kind of biologist.” For the next two decades, GFP remained just an interesting luminescent protein found in some species of marine animals. In 1989, scientists studied genes of ...

The simulated protein, named esmGFP, only exists as computer code, but contains the blueprint for a previously unknown type ...

In recent years, there has been a growing trend of an aging patient population and an increasing prevalence of age-associated diseases, underscoring the need for advancing research into the biological ...

Avoid fusions to the GFP fragments at the site of protein-protein interaction and consider optimizing the spacer length between the fusions and GFP fragments, if necessary. In the absence of ...

This enhanced temporal resolution surpasses that of conventional green fluorescence protein (GFP) systems, providing crucial insights into HIV-1 latency mechanisms and establishing a foundation ...

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Badran’s team investigated how codon location and usage affect quadruplet decoding with a modified superfolder green fluorescent protein (sfGFP), replacing a tyrosine codon at position 151 with a ...

Scientists from the University of Tokyo have identified a key aging marker for hematopoietic stem cells (HSCs), shedding light on how these cells undergo changes over time. Cluste ...