E1s and E2s first work generically across the cell to activate and prepare ubiquitin for attachment. E3 ligases then ensure that the tag is added to the right protein; as such, hundreds of specific ...

Acid reducing medicines from the group of proton pump inhibitors (PPIs) are best-selling drugs that prevent and alleviate ...

MIT neuroscientists have made a breakthrough in treating fragile X syndrome by leveraging a novel neurotransmitter signaling ...

This study presents an important discovery regarding the diversity and evolution of gall-forming microbial effectors. Supported by convincing computational structural predictions and analyses, the ...

All biological function is dependent on how different proteins interact with each other. Protein-protein interactions ...

DeepMind's AlphaFold, a generative AI tool, has achieved a milestone in biology by accurately predicting protein structures, ...

A new study shows that enhancing activity of a specific component of 'NMDA' receptors normalizes protein synthesis, neural activity and seizure susceptibility in the hippocampus of fragile X lab mice.

Northwestern University researchers have identified structural features in engineered cell receptors that correlate with ...

In  a  paper  published  on  aBIOTECH,  the  authors  revealed  the  joint  regulation  of  chromatin structure and gene expression by BMI1s, the core components of Arabidopsis PRC1, and the condensin ...

A team from the University of Washington led by Nobel laureate David Baker is using artificial intelligence to design ...

Evo 2 now includes information from humans, plants, and other eukaryotic species to expand its capabilities in generative functional genomics.

A research team co-led by scientists at the University of Arizona College of Medicine—Tucson found that an osteoporosis drug ...